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Search mechanisms in Duaer

In Duaer, search ChEMBL mechanisms of action by molecule with Duaer Data. One successful search uses 1 credit. This page includes the full English call skill.

What you get

Mechanisms in the Duaer data market returns ChEMBL mechanisms of action (type, target, max phase). One successful search uses 1 credit.

Add the node from the Duaer Data category (Mechanisms), or copy the skill on the data market. Related: Compounds and Indications.

Search on the canvas

  1. Open the node creator, select Duaer Data, then Mechanisms.
  2. Molecule is required (a new node starts with aspirin). Names or CHEMBL ids work.
  3. Limit defaults to 10, max 20; results prefer higher max phase. Select Execute step.

A successful search uses 1 credit. Production deliverables land in the data pool.

Call the API

  • GET https://api.duaer.com/v1/data/mechanisms?...
  • Authorization: Bearer <Duaer key>
  • molecule is required.

For keys, refer to Authentication for the Duaer public API. Below is the same English call skill as Copy skill.

Call skill

Same text as Copy skill on the Duaer data market. Keep it English.

---
name: duaer-mechanisms
description: >-
  Search ChEMBL mechanisms of action through Duaer by molecule.
  One successful search uses 1 Duaer credit.
---

# Duaer mechanisms

Search ChEMBL mechanisms of action through Duaer with a Duaer key.

## Call

`GET https://api.duaer.com/v1/data/mechanisms?molecule=aspirin&limit=10`

Header: `Authorization: Bearer <Duaer key>`

Use an account key or a model API key.

`molecule` is required.

- `molecule` — molecule name or ChEMBL id (`CHEMBL25`). Names resolve via ChEMBL search. Look up PubChem names with https://skills.duaer.com/compounds.md.
- `limit` — optional. From 1 to 20. Default 10. Results prefer higher max phase.

## Result

Each item has `source`, `title`, `url`, `summary`, `mechanismId`, `moleculeChemblId`, `mechanismOfAction`, `actionType`, `targetChemblId`, `maxPhase`, and `directInteraction`.
Reuse `moleculeChemblId` / names when searching compounds, activities, or indications. Reuse `targetChemblId` when searching activities or targets.

## Credits

One successful search uses 1 credit.
An empty search, a failed search, a compound that matches nothing, or no remaining credits uses 0.
No remaining credits returns 402 and does not search.
A missing key returns 401.

Questions

How are Duaer mechanism results ordered?

By max phase for the mechanism, highest first.

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