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Search drug–gene interactions in Duaer

In Duaer, search drug–gene interactions via DGIdb with Duaer Data. One successful search uses 1 credit. This page includes the full English call skill.

What you get

Drug–gene in the Duaer data market returns DGIdb interactions (gene, drug, type, score). One successful search uses 1 credit.

Add the node from the Duaer Data category (Drug–gene), or copy the skill on the data market. Related: Genes and Compounds.

Search on the canvas

  1. Open the node creator, select Duaer Data, then Drug–gene.
  2. Enter Gene (a new node starts with EGFR) or Drug (such as imatinib); both may be set.
  3. Approved is optional (yes/no). Limit defaults to 10, max 20; results prefer higher interaction score. Select Execute step.

A successful search uses 1 credit. Production deliverables land in the data pool.

Call the API

  • GET https://api.duaer.com/v1/data/drug-gene?...
  • Authorization: Bearer <Duaer key>
  • gene or drug is required.

For keys, refer to Authentication for the Duaer public API. Below is the same English call skill as Copy skill.

Call skill

Same text as Copy skill on the Duaer data market. Keep it English.

---
name: duaer-drug-gene
description: >-
  Search drug–gene interactions through Duaer via DGIdb.
  One successful search uses 1 Duaer credit.
---

# Duaer drug–gene

Search drug–gene interactions through Duaer with a Duaer key (DGIdb).

## Call

`GET https://api.duaer.com/v1/data/drug-gene?gene=EGFR&approved=yes&limit=10`

Header: `Authorization: Bearer <Duaer key>`

Use an account key or a model API key.

Provide `gene` or `drug` (or both).

- `gene` — gene symbol (e.g. `EGFR`).
- `drug` — drug name (e.g. `imatinib`).
- `approved` — optional. `yes` or `no` to keep only approved or unapproved drugs.
- `limit` — optional. From 1 to 20. Default 10. Results prefer higher interaction score.

## Result

Each item has `source`, `title`, `url`, `summary`, `gene`, `geneConceptId`, `drug`, `drugConceptId`, `approved`, `interactionTypes`, `interactionScore`, and `sources`.
Related genes: https://skills.duaer.com/genes.md.
Related compounds: https://skills.duaer.com/compounds.md.
Related targets: https://skills.duaer.com/targets.md.

## Credits

One successful search uses 1 credit.
An empty search, a failed search, a compound that matches nothing, or no remaining credits uses 0.
No remaining credits returns 402 and does not search.
A missing key returns 401.

Questions

Must I set both Gene and Drug in Duaer Drug–gene?

Provide at least one. Gene alone lists drugs for that gene; Drug alone lists genes for that drug.

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