入门
在 Duaer 里查 IMPC 小鼠表型
在 Duaer 里：国际小鼠表型联盟（IMPC）敲除小鼠的显著表型：表型术语、纯合/杂合、性别、p 值、效应量与检测项目。一次成功查询用 1 额度。
能拿到什么
Duaer 数据市场里的「IMPC 小鼠表型」：国际小鼠表型联盟（IMPC）敲除小鼠的显著表型：表型术语、纯合/杂合、性别、p 值、效应量与检测项目。查到结果时用 1 额度，结果交给数字组织的下一个节点。
从节点创建器选 Duaer 数据 → IMPC 小鼠表型，或打开 数据市场。相关：mgi、mp、phenotypes。
适合做什么
- 在靶点研究前查看某基因敲除后小鼠会出现什么表型。
- 查找敲除后会导致某表型（如眼部形态异常）的基因。
在画布里检索
- 打开节点创建器，选 Duaer 数据 → IMPC mouse phenotypes。
- 填 Gene（小鼠基因符号，如 Pax6）或 Phenotype（表型术语）。
- Limit 默认 10，最大 20。执行。
查到结果才扣 1 额度；没有结果、输入有误或上游失败都不扣。
用 API 调用
- GET https://api.duaer.com/v1/data/impc?gene=Pax6
- Authorization: Bearer <Duaer key>
下方是与数据市场「复制技能」相同的英文技能，含参数、示例与返回字段。
调用技能（英文）
与数据市场「复制技能」一致。
---
name: duaer-impc
description: >-
Duaer IMPC mouse phenotypes. Significant phenotypes of knockout mice from the International Mouse Phenotyping Consortium: phenotype term, zygosity, sex, p-value, effect size, and test.
One successful search uses 1 Duaer credit.
---
# Duaer IMPC mouse phenotypes
Duaer IMPC mouse phenotypes returns statistically significant genotype–phenotype calls from IMPC, strongest p-values first. It shows what happens in a mouse when a gene is knocked out.
## When to use
- Check what a knockout of a gene does in mice before a target study.
- Find genes whose knockout causes a phenotype, such as abnormal eye morphology.
## When not to use
- Curated mouse gene records and alleles. Use https://skills.duaer.com/mgi.md.
- Human disease phenotypes. Use https://skills.duaer.com/phenotypes.md.
## Call
`GET https://api.duaer.com/v1/data/impc?gene=Pax6`
Header: `Authorization: Bearer <Duaer key>`
Use an account key or a model API key.
Get a Duaer key: https://skills.duaer.com/keys.md
## Parameters
Provide `gene` or `phenotype`.
- `gene` — Mouse gene symbol, such as Pax6.
- `phenotype` — Optional. Mammalian Phenotype term name, such as abnormal eye morphology.
- `limit` — Optional. Rows to return, from 1 to 20. Default 10.
## Examples
- `GET https://api.duaer.com/v1/data/impc?gene=Pax6` — phenotypes of Pax6 mutants.
- `GET https://api.duaer.com/v1/data/impc?phenotype=abnormal%20eye%20morphology&limit=20` — genes with that phenotype.
## Result
The response is `{ "items": [...] }`. Each item has `source`, `title`, `url`, and `summary`, plus:
- `gene`, `mgiId` — mouse gene symbol and MGI id.
- `phenotype`, `mpId`, `topPhenotype` — Mammalian Phenotype term and its top-level class.
- `zygosity`, `sex`, `lifeStage` — which mice showed it.
- `pValue`, `effectSize` — statistics of the call.
- `allele`, `procedure`, `parameter`, `center` — allele and test details.
Fields without a value are left out.
## Credits
A search that returns at least one row uses 1 credit.
An empty search, a search that finds nothing, or a failed search uses 0.
Wrong input returns 400 with a message and uses 0.
No remaining credits returns 402 and does not search.
A missing key returns 401.
## Related
- https://skills.duaer.com/mgi.md
- https://skills.duaer.com/mp.md
- https://skills.duaer.com/phenotypes.md
常见问题
Duaer 的IMPC 小鼠表型检索扣多少额度？
查到结果时扣 1 额度；没有结果或出错不扣。
Duaer IMPC 能用人类基因符号吗？
请用小鼠符号，如 Pax6、Trp53；小鼠符号通常与人类相同，只有首字母大写。
同组