> For the complete documentation index, see [llms.txt](https://doc.duaer.com/zh/llms.txt). Markdown versions of documentation pages are available by appending `.md` to page URLs; this page is available as [Markdown](https://doc.duaer.com/zh/getting-started/impc.md).

# 在 Duaer 里查 IMPC 小鼠表型

在 Duaer 里：国际小鼠表型联盟（IMPC）敲除小鼠的显著表型：表型术语、纯合/杂合、性别、p 值、效应量与检测项目。一次成功查询用 1 额度。
## 能拿到什么

Duaer 数据市场里的「IMPC 小鼠表型」：国际小鼠表型联盟（IMPC）敲除小鼠的显著表型：表型术语、纯合/杂合、性别、p 值、效应量与检测项目。查到结果时用 1 额度，结果交给数字组织的下一个节点。

从节点创建器选 Duaer 数据 → IMPC 小鼠表型，或打开 [数据市场](/zh/getting-started/data-market.md)。相关：[mgi](/zh/getting-started/mgi.md)、[mp](/zh/getting-started/mp.md)、[phenotypes](/zh/getting-started/phenotypes.md)。

## 适合做什么

- 在靶点研究前查看某基因敲除后小鼠会出现什么表型。
- 查找敲除后会导致某表型（如眼部形态异常）的基因。

## 在画布里检索

1. 打开节点创建器，选 Duaer 数据 → IMPC mouse phenotypes。
2. 填 Gene（小鼠基因符号，如 Pax6）或 Phenotype（表型术语）。
3. Limit 默认 10，最大 20。执行。

查到结果才扣 1 额度；没有结果、输入有误或上游失败都不扣。

## 用 API 调用

- GET https://api.duaer.com/v1/data/impc?gene=Pax6
- Authorization: Bearer <Duaer key>

下方是与数据市场「复制技能」相同的英文技能，含参数、示例与返回字段。

## 调用技能（英文）

与数据市场「复制技能」一致。

```
---
name: duaer-impc
description: >-
  Duaer IMPC mouse phenotypes. Significant phenotypes of knockout mice from the International Mouse Phenotyping Consortium: phenotype term, zygosity, sex, p-value, effect size, and test.
  One successful search uses 1 Duaer credit.
---

# Duaer IMPC mouse phenotypes

Duaer IMPC mouse phenotypes returns statistically significant genotype–phenotype calls from IMPC, strongest p-values first. It shows what happens in a mouse when a gene is knocked out.

## When to use

- Check what a knockout of a gene does in mice before a target study.
- Find genes whose knockout causes a phenotype, such as abnormal eye morphology.

## When not to use

- Curated mouse gene records and alleles. Use https://skills.duaer.com/mgi.md.
- Human disease phenotypes. Use https://skills.duaer.com/phenotypes.md.

## Call

`GET https://api.duaer.com/v1/data/impc?gene=Pax6`

Header: `Authorization: Bearer <Duaer key>`

Use an account key or a model API key.

Get a Duaer key: https://skills.duaer.com/keys.md

## Parameters

Provide `gene` or `phenotype`.

- `gene` — Mouse gene symbol, such as Pax6.
- `phenotype` — Optional. Mammalian Phenotype term name, such as abnormal eye morphology.
- `limit` — Optional. Rows to return, from 1 to 20. Default 10.

## Examples

- `GET https://api.duaer.com/v1/data/impc?gene=Pax6` — phenotypes of Pax6 mutants.
- `GET https://api.duaer.com/v1/data/impc?phenotype=abnormal%20eye%20morphology&limit=20` — genes with that phenotype.

## Result

The response is `{ "items": [...] }`. Each item has `source`, `title`, `url`, and `summary`, plus:

- `gene`, `mgiId` — mouse gene symbol and MGI id.
- `phenotype`, `mpId`, `topPhenotype` — Mammalian Phenotype term and its top-level class.
- `zygosity`, `sex`, `lifeStage` — which mice showed it.
- `pValue`, `effectSize` — statistics of the call.
- `allele`, `procedure`, `parameter`, `center` — allele and test details.

Fields without a value are left out.

## Credits

A search that returns at least one row uses 1 credit.
An empty search, a search that finds nothing, or a failed search uses 0.
Wrong input returns 400 with a message and uses 0.
No remaining credits returns 402 and does not search.
A missing key returns 401.

## Related

- https://skills.duaer.com/mgi.md
- https://skills.duaer.com/mp.md
- https://skills.duaer.com/phenotypes.md

```
## Questions

### Duaer 的IMPC 小鼠表型检索扣多少额度？

查到结果时扣 1 额度；没有结果或出错不扣。

### Duaer IMPC 能用人类基因符号吗？

请用小鼠符号，如 Pax6、Trp53；小鼠符号通常与人类相同，只有首字母大写。

## 相关

- [在 Duaer 里检索 MGI](https://doc.duaer.com/zh/getting-started/mgi.md)
- [在 Duaer 里检索 MP](https://doc.duaer.com/zh/getting-started/mp.md)
- [在 Duaer 里检索表型](https://doc.duaer.com/zh/getting-started/phenotypes.md)